Prof. Dr. med. Dr. rer. nat. Klaus Hamprecht
Im Juni 2022 verstarb im Alter von 67 Jahren Professor Dr. med Dr. rer. nat. Klaus Hamprecht. Seit mehr als 30 Jahren bis zu seinem Lebensende war er am Institut für Medizinische Virologie und Epidemiologie der Viruskrankheiten am Universitätsklinikum Tübingen tätig und leitete als Oberarzt das Konsiliarlabor für kongenitale und postnatale Cytomegalievirus-Infektionen. Als Mitglied der Gesellschaft für Virologie engagierte er sich insbesondere für die klinische Virologie. Er gestaltete diese bis zuletzt durch unzählige aktive Beiträge mit und war ein weit bekannter und geschätzter Kollege.
Klaus Hamprecht studierte Biochemie und Medizin in München und Tübingen. 1986 schloss er seine naturwissenschaftliche Promotion am Friedrich-Miescher-Labor des Max-Planck-Institutes in Tübingen ab und 1988 seine Medizinische Dissertation. Es folgten Ausbildungsstationen am Universitätsklinikum Ulm, Robert-Bosch-Krankenhaus in Stuttgart und ab 1991 als Wissenschaftlicher Assistent am Institut für Medizinische Virologie der Universität Tübingen. Hier baute er die CMV-Diagnostik mittels molekularbiologischer Technologien und sorgfältig etablierter Zellkulturmethoden auf. 1995 erfolgte die Facharzt-Anerkennung, 2004 die Habilitation im Fachgebiet „Klinische Virologie“ und 2007 die Ernennung zum außerplanmäßigen Professor.
Schwerpunkte seiner wissenschaftlichen und klinischen Arbeit waren die Diagnostik von CMV-Infektionen in der Schwangerschaft, die konnatale und postnatale CMV-Transmission, sowie deren Prävention und Behandlung. Für die Abklärung von Virostatika-Resistenzen entwickelte er genotypische und phänotypische Untersuchungsmethoden, für die Prävention der Virustransmission durch Muttermilch ein patentiertes Virusinaktivierungsverfahren.
Er pflegte eine enge und äußerst fruchtbare Kooperation mit vielen klinischen Partnern, z. B. aus der Pränatalmedizin und der Neonatologie. Seine wissenschaftlichen Artikel, Buchbeiträge und Forschungsergebnisse werden national wie international wahrgenommen.
Unter anderem als Mitglied der Kommission “Virusinfektion in der Schwangerschaft” der DVV und GfV brachte er seine breite Expertise und äußerst detaillierte Literaturkenntnis bei der Erstellung verschiedener Leitlinien ein und trug maßgeblich zu einer verbesserten Patientenversorgung und breiten Sichtbarkeit der klinischen Virologie bei. Die Laborleitertreffen und den Arbeitskreis für klinisch-virologische Forschung der GfV hat er mit seiner Teilnahme stets bereichert.
Klaus Hamprecht war ein hervorragender Dozent und begeisterter Mentor für mehrere Generationen Studierender, Doktorandinnen und Doktoranden verschiedener Fachrichtungen sowie Kollegen und Kolleginnen in der Weiterbildung. Die individuelle Betreuung und Beratung von Patientinnen im Rahmen seiner Tätigkeit für das Konsiliarlabor waren ihm als Arzt immer ein sehr wichtiges Anliegen. Durch sein tiefgehendes Fachwissen war er ein sehr geschätzter Ansprechpartner, auch weit über die Grenzen des Universitätsklinikums Tübingen hinaus.
Sein genuines Interesse am Gegenüber, seine Lebensfreude und Humor prägten sein gesamtes persönliches Auftreten.
Wir bedauern es zutiefst, mit Klaus Hamprecht einen hochgeschätzten Kollegen, großartigen klinischen Virologen und stets hilfsbereiten Freund verloren zu haben.
Unsere Anteilnahme gilt seiner Familie und Angehörigen.
Tina Ganzenmüller, Stefan Jürgens und Thomas Iftner für das Kollegium des Instituts für Medizinische Virologie, Universitätsklinikum Tübingen und die Gesellschaft für Virologie
Prof. Dr. med. Hans-Dieter Klenk
25 June 1938 in Cologne
† 1. Juni 2021 in Giessen
The Society of Virology mourns the death of its founding member and former President Professor Hans-Dieter Klenk Hans-Dieter Klenk studied medicine and biochemistry in Tübingen, Vienna and Cologne. From 1967 to 1970 he was a visiting scientist in Purnell Choppin's laboratory at the Rockefeller University in New York. Back in Germany, he was appointed C3 professor at the Justus Liebig University in Giessen in 1973 and in 1985 he accepted a call to the chair of virology at the Philipps University in Marburg and became director of the Institute of Virology. He held this position until his retirement in 2007.
Hans-Dieter Klenk has decisively shaped Marburg virology and virology in Germany and established its international orientation and visibility. Under his leadership, numerous young scientists had the opportunity to develop their own scientific profile and to be appointed to leading positions nationally and internationally.
Hans-Dieter Klenk's name is closely associated with his very successful research on influenza viruses, especially the role of surface proteins, haemagglutinin and neuraminidase in the pathogenesis of influenza. Furthermore, other zoonotic viruses that threaten public health as emerging viruses were of great interest to him. Here he was able to establish a new research direction in Marburg virology, which is still very actively pursued today.
He led numerous coordinated programmes of the German Research Foundation, including the SFB 286, and was active as a board member for many scientific advisory boards of research institutions (Georg-Speyer-Haus, Frankfurt am Main, Feldberg Foundation for Anglo-German Scientific Exchange, Institute of Medical Microbiology, Fudan University). He was a founding member of Society of Virology and led the society as president from 1999 to 2005. In 2015, he received the Loeffler-Frosch Medal of Society of Virology for his special services to virology in German-speaking countries. He has served as Vice-President of the von Behring-Röntgen-Stiftung, Gießen-Marburg, since its foundation.
Hans-Dieter Klenk has received numerous highly respected scientific prizes, such as the Robert Koch Medal, the Ernst Jung Medal for Medicine and the Emil von Behring Prize. He was also awarded the Federal Cross of Merit 1st Class in 2018.
Hans-Dieter Klenk's personality was characterised by his natural authority coupled with astuteness and precision. With him, virology in Germany loses one of its great personalities who shaped the scientific landscape for decades and who was a valued advisor to the end.
We miss the excellent scientist and the straightforward, consistent and generous person and will keep him in lasting memory.
Prof. Dr. med. habil. leopold Döhner
25 November 1932
† 20 May 2021
Leopold Döhner, founding member and first Vice-President of Society of Virology, passed away in his eighty-ninth year. His research focused on respiratory viral infections, especially those caused by influenza and adenoviruses. As early as 1975, coming from the Medical Academy in Magdeburg, he was appointed Professor of Medical Microbiology at the University of Greifswald. There he headed the institute of the same name - whose foundation goes back to Friedrich Loeffler - until 1992.
In 1993, he founded the Private Institute for Microbiological Research - MICROMUN GmbH in Greifswald, with which he remained associated in an advisory and friendly capacity until his death. Leopold Döhner was an extremely pleasant colleague who combined scientific determination with great personal modesty. Despite his many obligations as a university lecturer, as chairman of the Society for Microbiology and Epidemiology of the GDR and in many other tasks, he did not allow himself to be deprived of his personal experimental work - in other words, to preserve his roots in the laboratory. In this way, he was able to awaken enthusiasm for virological research in generations of students.
The Society of Virology will honour his memory.
Detlev H. Krüger, Berlin
Photo: Berlin-Brandenburg Academy of Sciences and Humanities
Prof. Dr. med. Gisela Enders
25 May 1924 in Stuttgart
1 May 2021 in Stuttgart
A life for medical virology (1924 - 2021). On 1 May 2021, Prof. Dr. med. Gisela Enders, a pioneer of medical virology, passed away in her home town of Stuttgart. We are filled with grief and respect and look back on her life's work, which at the same time provides an insight into the development of virology in Germany as an independent subject in science, university teaching and medicine.
Mrs Enders was born Gisela Ruckle on 25 May 1924 in Stuttgart and grew up as a true Swabian: she was hard-working, inventive, shrewd, persistent, caring and assertive. Studying medicine was her great desire. Independently, she transferred to a grammar school at the age of 15 and, after graduating from high school, studied medicine in Munich and Tübingen from 1943 to 1949 (doctorate in 1953). Under wartime conditions she did nursing service in a military hospital. After various intermediate stations as a guest assistant at the University Children's Hospital in Cambridge and as a scientific assistant in Heidelberg at the Institute for Virus Research, she took the opportunity to become acquainted with the latest developments in medicine and infectiology in the USA from 1953 - 1956. At that time, combating epidemics was a fateful, worldwide challenge, especially with regard to the aetiologically still largely unexplored viral diseases. There were still no functioning vaccinations against influenza, poliomyelitis, measles and others. The seemingly harmless children's disease rubella was not recognised as a cause of embryopathies and fetopathies until 1941. Laboratory analyses and pathogen isolation were lacking. In America, the young German doctor succeeded, among other things with a Fulbright Fellowship, in becoming an employee in the laboratories of American virology pioneers, first with Dr. J. Salk (Pittsburgh), who developed the first polio vaccine, and then with Dr. J.F. Enders (Harvard, Boston), who, together with other researchers, established cell culture technology to isolate pathogenic viruses and grow them in any quantity. This was the decisive breakthrough for the production of vaccines, the production of antigens for routine serodiagnosis and immunity determination, the analysis of virus replication and the development of a specific therapy.
Already in Salk's laboratory, Gisela Enders isolated the measles monkey virus from monkey kidney cells. In the group of J.F. Enders, she then discovered the close relationship between the measles monkey virus and the human measles virus. There was no relationship to the Nobel Prize winner J.F. Enders. But: "Nomen est omen", because Mrs. Ruckle received the name Enders in 1957 by marrying Dr. Gerhard Enders in Germany.
For Ms Enders, the path as a woman and German in the USA was doubly difficult. With great commitment and tireless diligence, she contributed a great deal to the development work in the burgeoning field of virology and additionally helped to break down prejudices with her winning manner.
In 1956, Ms Enders returned to Europe. Initially, she was involved in setting up the production of vaccines against rubella and measles at the Institut Mérieux in Lyon. Together with other US returnees, she contributed to the technology transfer that enabled the rise of virology in Germany to a top level. As a research associate at the Hygiene Institute of the University of Marburg, she built up a powerful virus diagnostics unit. She quickly gained a high reputation among the medical profession in and outside the university hospital as a competent contact person and advisor. Her lively disposition, her clear statements and her willingness to take responsibility in the event of clinical problems or in the fight against epidemics, as well as her extensive knowledge, quickly won her great and lifelong recognition and made her a sought-after author of medical book and journal articles at an early stage.
In 1963, Mrs Enders moved with her husband, the orthopaedic surgeon Dr Gerhard Enders, to Stuttgart, the city that became the centre of life for Gisela and Gerhard Enders and their two sons Christoph and Martin. There she joined the Stuttgart State Medical Examination Office, set up a modern department for virus diagnostics and rose to the position of Government Medical Director. In 1973, she habilitated and received an honorary professorship first in Marburg in 1976 and then in Stuttgart in 1984.
Scientifically, she increasingly turned to the problem of infections with rubella and other viruses that endanger pregnancy and the foetus. She felt increasingly restricted in her research work in the civil service. In 1979, as a medical specialist for medical microbiology and infectious disease epidemiology, she founded her own laboratory practice with a focus on virology at great entrepreneurial risk. The company was a resounding success. It grew quickly and is now a large institute covering all branches of laboratory medicine with the most modern methods and is run by a community of several laboratory physicians as a medical care centre. With untiring energy, Mrs Enders has always led her institute innovatively and adapted it to all new diagnostic developments. Outstanding was the unusually close and trusting contact with the medical profession. This enabled her to conduct unusually large and consistent scientific studies in her main field of work, perinatal medicine. She has published her findings in many international journals of virology and German journals of continuing medical education and book contributions. Her book "Infections and Vaccinations in Pregnancy" (1991) became the infectiological "bible" of gynaecology and perinatal medicine. In addition, she wrote numerous original papers on the entire spectrum of endemic and emerging viral diseases and continued to be involved in clinical virology in national and international professional societies. Here, among others, the Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten e. V. (German Association for the Control of Viral Diseases) should be mentioned. (DVV), which was founded soon after Ms Enders' return from the USA by the German federal states to provide scientific advice (initially on the problem of poliomyelitis). For the first time, the DVV provided clinical virology, paediatrics and the public health service with a forum in which virological experts in Germany could consult and exchange practical experience. Rarely have so many chair holders and heads of department pipetted together, often with the assistance of Gisela Enders. She was able to draw from a bubbling source for this, the "European Group for Rapid Viral Diagnosis", which she co-founded and of which she became an honorary member. By merging with the "European Association against Poliomyelitis and Other Viral Diseases", this later became the "European Society for Clinical Virology" (ESCV). Mrs Enders continued to run her highly recognised laboratory institute into old age, in which her son Priv.-Doz. Dr. Martin Enders took her place a few years ago and continues her life's work.
Gisela Enders prevailed against all odds and was always recognised and admired as a scientist, clinician and entrepreneur. Her work has been honoured many times with national and international prizes, orders and honorary memberships, including the Federal Cross of Merit on Ribbon for achievements in the field of viral research, the Haackert Gold Medal for services in the field of prenatal diagnostics, the Albert Schweitzer Medal and the Maternité Award of the German Society for Perinatal Medicine. In 2011, she was honoured with the Loeffler Frosch Medal of the Society of Virology for her life's work.
With Gisela Enders we lose the grande dame of clinical virology. As a pioneer, she decisively shaped this field by combining patient-oriented diagnostics and scientific activity. With her selfless and benevolent manner, she always supported and promoted her institute team as well as her colleagues near and far and was thus not only highly respected as a scientist, but also extremely appreciated and popular as an advisor and friend across generations.
We will miss her and keep her in our lasting memory.
Hans W. Doerr
Professor Dr. med. Bernhard Fleckenstein
10 August 1944 in Würzburg
04 May 2021 in Schlaifhausen, Wiesenthau
The Society of Virology mourns the death of its founding president, Professor Bernhard Fleckenstein. From 1978 until his retirement in 2015, Bernhard Fleckenstein held the Chair of Virology at the Friedrich-Alexander University of Erlangen-Nuremberg and was Director of the Virological Institute at the University Hospital Erlangen. After studying medicine in Freiburg/Br and Vienna from 1963 to 1969, a period as a medical assistant in Lübeck and a doctorate in virology, he began his virological research work in 1970 at the Institute for Hygiene and Microbiology at Göttingen University (Director: Prof. Reiner Thomssen).
In 1972, he joined Prof. Harald zur Hausen's group at the Institute of Clinical Virology at the Friedrich-Alexander University of Erlangen-Nuremberg, where he habilitated in 1975. In 1976, he was appointed Associate Professor of Microbiology and Molecular Genetics at Harvard Medical School in Boston and became head of the Department of Microbiology at the Primate Center of Harvard University. In 1978, he was appointed Full Professor and Head of the Institute of Clinical and Molecular Virology at the University of Erlangen, where he taught until 2015 following rejected appointments to the chairs of virology at the University of Freiburg (1987) and the Ludwig Maximilian University of Munich (1987). He also turned down a call to the position of Scientific Member and Chairman of the Foundation Board of the German Cancer Research Centre in 2003. His work in Erlangen was also characterised by the continuous structural development of the virological diagnostics and research laboratories into a nationally and internationally renowned centre for clinical and molecular virology.
Already in his first year of virological work in Göttingen, Bernhard Fleckenstein turned to the newly discovered group of rhadinoviruses, a subgroup of herpes viruses with oncogenic properties. He continued this work after moving to Harvard Medical School in Boston. He investigated the molecular mechanisms of the lymphomas and lymphatic leukaemias caused by these viruses and was able to publish in Nature as early as 1978 that isolated viral DNA has a tumourigenic effect in animal experiments. He and his working group in Erlangen achieved another important breakthrough in this field when they published in 1992 that individual representatives of this virus group can immortalise human T cells in cultures, i.e. stimulate them to grow continuously. This methodologically paved the way for a better analysis of central signalling pathways in lymphocytes and led to a large number of collaborative projects in which fundamental mechanisms of T cell activation were elucidated. In further pioneering work, Bernhard Fleckenstein and his colleagues dealt with the human cytomegalovirus, an important pathogen of prenatal infections and of infections in immunosuppressed individuals. They cloned the entire genome of the virus for the first time and carried out the molecular mapping of the most important structural and regulatory proteins. In collaboration with Prof. Walter Schaffner, University of Zurich, Bernhard Fleckenstein discovered the enhancer of cytomegalovirus, which is now used worldwide for the expression of eukaryotic genes in cell culture, in transgenic animals and for somatic gene therapy trials. At his institute, Bernhard Fleckenstein established a broad research programme on the molecular biology of herpes viruses, papillomaviruses and retroviruses, which was supported by a large number of young junior scientists. The Funding of young scientists was always a special concern for Bernhard Fleckenstein, which he never lost sight of, even in his function as spokesperson for the Collaborative Research Centre 466 "Lymphoproliferation and Viral Immunodeficiency" (from 1996 to 2008) and the Research Training Group 1071 "Viruses of the Immune System" (from 2005 to 2013).
From 1997 to 2001 and from 2005 to 2008 Bernhard Fleckenstein was Dean of the Faculty of Medicine at the University of Erlangen-Nuremberg. In this function he set the course for a performance-oriented university medicine in Erlangen. He was the founding president of the German Society of Virology and a founding member as well as the first Secretary General of the European Society for Virology. Bernhard Fleckenstein was a member of numerous national and international scientific bodies, including the Academy of Sciences and Literature in Mainz and the German National Academy Leopoldina. His awards include the Max Planck Prize (1991), the Aronson Prize of the State of Berlin (1991), the Ludwig Aschoff Prize of the University of Freiburg (2004) as well as the Cross of Merit on Ribbon of the Order of Merit of the Federal Republic of Germany (2003) and the Bavarian Order of Merit (2006).
Bernhard Fleckenstein also impressed as a personality with his always positive charisma, enthusiasm, generosity and strategic foresight. Due to his energetic and unselfish Funding of young academics, many of his students were appointed to virological chairs and professorships both nationally and internationally. He co-founded Society of Virology and shaped it like no other. With him we lose a great and tireless promoter of virology in Germany and a wonderful colleague.
We will keep Bernhard Fleckenstein in lasting memory.
Klaus Überla and Thomas Stamminger
Prof. Dr Günther Keil
1953 in Großenhain
18 February 2020 in Templin
Günther Keil was born in 1953 in Großenhain near Dresden and grew up in Singen am Hohentwiel. He studied biology in Constance, where he graduated in 1978 with a thesis on nuclear-associated protein kinases under Rolf Knippers, the doyen of molecular biology research methods in Germany. He completed his doctoral thesis in Erlangen with Bernhard Fleckenstein, where he worked on herpes viruses, which were to remain his main field of work in the future. In 1981, he joined Ulrich Koszinowski's research group at the Federal Research Centre for Viral Diseases of Animals (now the Friedrich Loeffler Institute) in Tübingen, from where he moved to the island of Riems near Greifswald in 1995.
hile working on primate herpesviruses in Erlangen, he continued his molecular biology studies with murine cytomegalovirus in Tübingen. He then turned his attention to bovine herpesviruses. In recent years, his research activities then focused on the African swine fever virus. Not only these DNA viruses, but also RNA viruses such as the hepatitis A virus, pneumoviruses, flaviviruses or influenza A viruses were among his objects of investigation. His questions related to virological, immunological, methodological and diagnostic aspects as well as to the development of vaccines. He was particularly interested in elucidating the function of viral proteins, enhancing antigen presentation to stimulate T-cell response, manipulating viral genomes for attenuation, and deletion and vector vaccines. He was not a mainstream scientist, but over 150 publications, including in Science and PNAS, attest to his successful scientific work and over 50 co-authors document his successful involvement in the scientific community.
As director and professor as well as deputy director of the Institute for Molecular Virology and Cell Biology at the Riems Institute, he helped to rebuild it and was responsible for biological safety. He was always ready to give advice and support to his colleagues and selflessly shared his immense experience with others.
Günther Keil trained a large number of young scientists. He was an important point of orientation for his students and scientific companions. His enthusiasm for virological issues was contagious and as an experimenter he was a great role model. He expected the full commitment he showed from his students as well, but always supported them regardless of their success. One could learn from him the critical examination of data, especially one's own, as well as a straightforward attitude. His manner was modest and unconventional, but firm. With Günther Keil, we have lost a committed scientist, a highly esteemed colleague and a good friend. Our sympathy goes to his family and friends.
Thomas C. Mettenleiter and Andreas Dotzauer
Prof. Dr Christian Kunz
13 October 1927 in Linz
12 April 2020 in Vöcklabruck
On Easter Sunday, 12 April, Christian Kunz passed away at the age of 93. He was the founder and long-time director of the Institute of Virology at the Medical Faculty of the University of Vienna (now the Medical University of Vienna) and goes down in medical history as a pioneer and formative figure in the development of virology in Austria and as the father of the TBE ('tick') vaccine.
Christian Kunz was born in Linz on 13 October 1927, studied medicine in Vienna and Innsbruck after the Second World War and joined the Institute of Hygiene at the University of Vienna after obtaining his doctorate in 1954. Initially he worked as an unpaid visiting physician, then as a research assistant. Virology presented itself to the young Christian Kunz in the 1950s as an emerging field of research with many technological innovations and groundbreaking developments, such as the use of cell cultures for virus propagation and the development of polio vaccines.
His scientific interest in virology was encouraged by his boss, Richard Bieling, who enabled him to study at the then strongholds of virology in Germany with top researchers in Freiburg, Tübingen and Marburg. Kunz thus became acquainted with the state of the art in modern virus research at that time and returned to Vienna with great enthusiasm (and equipped with cell cultures for his scientific work). It was precisely at this time that the Vienna Institute had succeeded in isolating a virus as the causative agent of the initially puzzling so-called 'Schneider's' disease, which occurred frequently in the south of Vienna. This virus was then called the early summer meningoencephalitis (FSME) virus and was subsequently at the centre of Christian Kunz's research life.
His publications soon attracted international attention and he was invited to continue his research at the Rockefeller Laboratories in New York with a grant from the Rockefeller Foundation. Thus, in 1961-62, he came to a research institution that was virtually packed with leading virologists of the time and met Max Theiler, among others, who had received the Nobel Prize for Medicine in 1951 for the development of the yellow fever vaccine. This research stay and the contact with outstanding scientists shaped his further career.
Back in Vienna, he was entrusted by Hans Moritsch, the new director of the Hygiene Institute, with the management of a newly established virus department and, using his knowledge acquired in the USA, established a research focus in the field of arthropod-borne viruses (ARBO viruses). The TBE virus also played a central role in this phase. For the time, extremely innovative techniques of specific diagnostics were developed, the circulation of the virus in nature was researched and the sites of human infection in Austria (keyword 'tick map') were determined.
After the death of Hans Moritsch, Heinz Flamm became head of the Institute of Hygiene and made it possible to found a separate Institute of Virology, of which Christian Kunz was appointed head as full professor of virology in 1971. His work on the epidemiology of TBE made clear to him the extent of TBE as by far the most common virus-related disease of the central nervous system in endemic areas and prompted him to use his knowledge to develop a vaccine. This effort, first in cooperation with an English research institute and later with the Austrian pharmaceutical company Immuno, was crowned with great success and led to the production of a highly effective vaccine. Its widespread use brought about an impressive decline in TBE in Austria. As an anecdote, it should be mentioned that he and his colleague at the time, Hanns Hofmann (who has also unfortunately passed away), administered the first experimental vaccine to each other and were relieved to find that it was well tolerated after a few weeks.
The development of the TBE vaccine is probably the achievement with which the name of Christian Kunz is most strongly associated. However, his significance for the development of virology in Austria and in Europe is much broader, especially through his dedicated work in the field of virus diagnostics and medical virology. In 1975 he was a founding member and later for many years chairman of the 'European Group for Rapid Virus Diagnosis', an association of leading medical virologists from several European countries who were primarily concerned with the development of new methods for the early detection of viral infections. This gave viral diagnostics a new and relevant significance for the clinical care of patients. The quality of the impulses set was outstanding, so that this association (which since 1997 has become the 'European Society for Clinical Virology') was able to take on a pioneering role worldwide at that time. Christian Kunz was the chairman of the Austrian Society for Hygiene, Microbiology and Preventive Medicine for several years and a highly respected expert in numerous national and international committees, who put his expertise at the service of health policy decisions. In the mid-1980s, for example, he made a major contribution to the adoption of an evidence-based rather than fear-based approach to the then new problem of HIV infections in Austria.
In 1996 Christian Kunz became emeritus and in 2006 he was awarded the Loeffler Frosch Medal of the international 'Society of Virology' for his outstanding services to the development of virology in the German-speaking world. In recognition of his special achievements, he had already received the Medal of Honour in Gold from the Federal Capital Vienna in 1988, and he was also an honorary member of various national and international scientific societies. One of his great abilities was to bring about a symbiosis of medical-virological research and virus diagnostics with basic molecular research at his institute that was fruitful for all parts. He did this as a leader in a way that almost always made work a pleasure for his staff. This was mainly due to his always benevolent, supportive, encouraging and trusting attitude towards the abilities of his staff, as well as his - even in difficult times - never-ending and contagious sense of humour. I personally and many others who had the good fortune to work with him are grateful not only for his scientific achievements, but also for his generosity, human greatness and friendship.
Franz X. Heinz, oUnivProf. iR, Centre for Virology, Medical University of Vienna
Prof. Dr Michael F.G. Schmidt
17 February 2019
The Society of Virology mourns the death of Michael Schmidt, who passed away on 17.02.2019 at the age of 73.
He began his scientific career in Giessen, where, after studying biology at the Institute of Virology, he did his doctorate under Christoph Scholtissek on the glycosylation of viral glycoproteins. With the help of specific inhibitors, he gained insights into the functional significance of these carbohydrate structures, about which little was known at the time.
During a subsequent DFG-funded research stay at Washington University in St. Louis, USA, he was able to show for the first time that viral glycoproteins are cotranslationally acylated and that this modification is crucial for their membrane anchoring and fusion activity.
He continued this work at the Giessen Institute from 1980 and completed his habilitation there in the subjects of virology and biochemistry at the Department of Veterinary Medicine. In 1986 he accepted a professorship at the University of Kuwait, which he had to give up in the wake of the Kuwait crisis in 1990.
Back in Germany, he took over as head of the Institute for Immunology and Molecular Biology of the Department of Veterinary Medicine at the Free University of Berlin. Here he successfully continued his investigations into the functional significance of postsynthetic modifications of viral envelope proteins and studied the influence of probiotic bacteria on immunity and virus replication. Several of his publications have been cited several hundred times in the scientific literature.
Michael Schmidt has always taken on overarching responsibility, for example as Dean of his department at the FU or in his home community of Seddiner See 40 km southwest of Berlin: here he founded an association to take over the disused village shop in order not to let supply, communication and culture disappear from the village.
All who knew him will have fond memories of his infectious cheerfulness and joy in science.
Hans-Dieter Klenk, Marburg
Detlev H. Krüger, Berlin
Prof. Dr. rer. nat. Nikolaus Müller-Lantzsch
29 March 1943 in Görlitz/Neisse
02 August 2017 in Homburg/Saar
The Society of Virology mourns the death of its former president Professor Dr. rer. nat. Nikolaus Müller-Lantzsch
Nikolaus Müller-Lantzsch held the Chair of Virology at the University Hospital Homburg/Saar until his retirement in 2009.
Nikolaus Müller-Lantzsch was one of the founding members of Society of Virology and was its president from 2005 to 2011. Nikolaus Müller-Lantzsch studied biology at the universities of Hamburg and Freiburg from 1964 to 1971.
After obtaining his doctorate (Dr. rer. nat.) in 1974 with a thesis on transcription in SV40 and polyomavirus at the then Hygiene Institute (Department of Virology) of the University of Freiburg under the supervision of Prof. Richard Haas and Prof. Gerhard Brandner, Nikolaus Müller-Lantzsch worked at the Salk Institute, La Jolla, CA, USA, on the function of virus-specific RNA of the Moloney leukaemia virus. From 1976, he did postdoctoral research at the Institute of Virology at the University of Freiburg under the supervision of Prof. Dr. Harald zur Hausen. In 1981, he completed his habilitation ("Biochemical Characterisation of Epstein-Barr Virus Specific Antigens") at the Medical Faculty of the University of Freiburg. In 1980-1982 he was head of the department 'Research and Development Virology' at the Swiss Serum and Vaccine Institute in Bern. After being appointed to a C2 professorship at the Institute of Virology at the University of Fribourg in 1982, he took up a C3 professorship and the position of Department Director of the Virology Department at the Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar in 1988. In 1995 he was appointed C4 professor. Under his direction, a new institute building was constructed in Homburg and the prerequisites for the appointment as National Reference Centre for γ-herpesviruses were created. In the medical faculty of Saarland University, he held various offices of academic self-administration and was, among other things, dean and dean of studies of the medical faculty from 1998 to 2004. In 2002, he was appointed "Chevalier dans l'Ordre des Palmes académiques" by the French Prime Minister for his services with regard to scientific exchange with French colleagues.
One focus of Nikolaus Müller-Lantzsch's work after 1982 in Freiburg was the molecular biological characterisation of the EBV-encoded proteins EBNA-1, EBNA-2 and LMP and their significance for the biology of EBV. This complex of topics was also pursued by him in Homburg with great emphasis and supplemented by very comprehensive efforts to make these antigens useful in particular for the diagnosis of EBV reactivations. Systematic studies on EBV viral load complemented this important approach. During his time in Freiburg, Nikolaus Müller-Lantzsch made great contributions to the establishment of HIV diagnostics. Companions from this time will remember that the first series of HIV-positive preparations for HIV antibody immunofluorescence (especially the rapid tests necessary in transplantation medicine) were made by him in order to evaluate and demonstrate the feasibility and safety of the preparation. It is also worth mentioning that he was instrumental in designing and establishing computer-assisted virus diagnostics in Freiburg.
In addition to studies on EBV, he focused his scientific work from 1993 onwards on research into human endogenous retroviruses. In a fundamental work, he succeeded in proving that the human endogenous retrovirus HERVK (HML-HOM) has complete open reading frames. In further work, he was able to show that patients with germ cell tumours develop antibodies against viral proteins and that the tumour cells express the viral genes. Finally, the oncogenic potential of HERVK-encoded proteins could be demonstrated in mouse experiments. A large number of national and international collaborations document the high scientific value of this work. Collaboration with scientists from the GDR and Russia was particularly close to his heart. In the course of his work, he supervised a large number of diploma, doctoral and post-doctoral theses. In addition to his research activities and work in various expert committees, the establishment and continuous improvement of the latest diagnostic analysis methods in the context of patient care was an important concern for him.
Nikolaus Müller-Lantzsch was not only highly respected in virology as a scientist, but also extremely valued and popular as a colleague and friend. He always had more in mind than his own research topics and his personal successes. His ability was to see the big picture, seek responsibility and take leadership. This made him a distinguished chair and an outstanding president. We will keep him in lasting memory.
Friedrich Grässer, Homburg
Georg Bauer, Hartmut Hengel and Dieter Neumann-Haefelin, Freiburg
Prof. Dr Reinhard Kandolf
10 September 1948
31 March 2017 in Tübingen
A researcher at heart
Obituary: The virologist, pathologist and native of the Palatinate, Reinhard Kandolf, died completely unexpectedly at the age of only 68.
Prof. Reinhard Kandolf was head of molecular pathology in Tübingen. His field of work was viral myocarditis
(especially picornaviruses). On 31 March 2017, Prof. Reinhard Kandolf, Medical Director of the Department of Molecular Pathology at the University Hospital Tübingen, passed away completely unexpectedly in Tübingen.
Reinhard Kandolf was born on 10 September 1948 in the Upper Palatinate. After attending a humanistic grammar school, he studied medicine at the universities of Erlangen and Munich. His interest in research on the heart was awakened during his doctorate at the Medical Clinic I of the University of Munich under Professor Gerhard Riecker. As a scholarship holder and later research assistant at the Max Planck Institute (MPI) for Biochemistry in Mattinsried in the Department of Virus Research (1981-1993) with Professor Peter Hans Hofschneider, he succeeded for the first time in cloning coxsackievirus B3, a common pathogen of myocarditis.
In 1988, after his habilitation in Experimental Medicine at the Medical Faculty of the University of Munich, he received an endowed professorship in Medical Research at the MPI in Martinsried and then obtained his specialist qualification in Biochemistry. In 1993 he moved to Tübingen as C3 Professor of Molecular Pathology. This was followed by an appointment as Medical Director to the newly established C4 Professorship of Molecular Pathology at the University of Tübingen in 1997, which he held until his sudden death.
His scientific focus was on the field of cardiopathology. Together with his working group and numerous national and international co-operating partners, he published 300 scientific papers, many in highly renowned scientific journals. His scientific work has been honoured by various awards such as the Max Planck Research Prize for international cooperation in the field of viral aetiology of cardiovascular diseases and by the award of a visiting professorship at the Universita degli Studi di Roma Tor Vergata.
Reinhard Kandolf was also closely associated with the German Societies of Pathology, Cardiology and Paediatric Cardiology for many years. He was active in various positions in the Medical Faculty of Tübingen for many years.
With the death of Reinhard Kandolf, the University Hospital of Tübingen, German pathology and cardiology have lost an extraordinary person, a formative personality and an outstanding scientist. In his human way, Reinhard Kandolf accompanied many students as a mentor on their way into research and patient care. All who knew him will remember him with gratitude.
Prof. Karin Klingel,
Deputy Medical Director,
Department of Molecular Pathology
University Hospital Tübingen
Prof. Thomas Mertens, Ulm University Hospital
Image: Archive image University Hospital Tübingen
Prof. Dr. Dr.h.c.mult. Marian Horzinek
3 October 1936 in Katowice
28 July 2016
Obituary Prof. Dr. Dr.h.c.mult. Marian Horzinek
Prof. Marian Horzinek was a precious specimen of the already almost forgotten species of the polyglot and urbane universal scholar.
He studied veterinary medicine in Giessen and Hanover. After intermediate stations in Venezuela and Tübingen, he became head of department and professor of virology and viral diseases at Utrecht University, where he subsequently headed the Institute of Veterinary Research and the Graduate School of Animal Health.
Prof. Horzinek's research dealt with many aspects of virology, immunology and vaccinology and was reflected in more than 300 publications and 30 textbooks. His special scientific focus was on coronaviruses and infections in cats. In addition, he was an excellent teacher with numerous successful students - for example, his very first doctoral student was the renowned virologist Prof. Albert Osterhaus and his colleagues were appointed to more than 10 chairs of virology. The authors of this obituary are also indebted to Prof. Horzinek.
In addition to visiting professorships at Cornell University and the University of California Davis, Prof. Horzinek has been awarded honorary doctorates (Ghent, Hanover, Uppsala, Vienna, Guelph) and a variety of other prizes. He served as editor, president and founding member of several veterinary professional organisations and journals. In addition, he contributed his valuable experience as a long-standing board member of the scientific advisory boards of universities in Vienna and Barcelona.
Prof. Horzinek could philosophise excellently and present complex and also controversial topics in a pointed and eloquent manner. As a veterinarian and scientist, he was particularly concerned with bringing clinics and research closer together and beating the drum for fact-based medicine. In this sense, he was an early pioneer and eloquent advocate for "precision medicine", which is on everyone's lips today. His farsightedness, his immense horizon of knowledge, his critical-constructive spirit and, last but not least, his mischievous and extraordinary humour full of etymological allusions, anecdotes and poetry remain unforgotten.
Dr. med. vet. Andreas Bergthaler
CeMM Research Centre for Molecular Medicine, Vienna
Dr. med. vet. Andreas Pichlmair
Max Planck Institute for Biochemistry, Munich
Prof. Dr. med. Hans Joachim Eggers
26 July 1927 in Baumholder-Nahe
05 May 2016 in Cologne
The Society of Virology mourns the loss of
Professor Dr. med. Hans Joachim Eggers
Hans Joachim Eggers held the Chair of Virology at the University of Cologne until his retirement in 1994.
Hans Joachim Eggers was an important virologist "of the first hour" in Germany. Already during his work in the United States, he was one of the founders of research in the field of selective antiviral therapy (1963). Numerous publications on antiviral chemotherapy and resistance formation resulted from this work, in which the hypothesis was also formulated that the combination of two substances against different target structures should be used to reduce resistance selection.
Furthermore, essential fundamental findings on RNA and protein synthesis in picornaviruses (especially polioviruses), on pathogenicity factors and on the development of the cytopathic effect, which were obtained for the first time by molecular biology, can be traced back to his research results. As a virologist and physician, he has also regularly worked on clinical virological issues. The high international recognition of his work is expressed not least in the fact that 26 of his approximately 200 publications have appeared in the best interdisciplinary journals (Nature, Science, PNAS, J Exp Med, Lancet).
Born into a pastor's family in Baumholder, Hans Joachim Eggers studied medicine at the universities of Cologne and Heidelberg from 1947-1953 after graduating from high school in Sobernheim. He began his scientific work at the Biochemistry Department in Cologne as a doctoral student of Prof. Dr. Dr. h.c. Ernst Klenk. His love for virology was already awakened during his work at the University Neurology Clinic in Cologne (1953-1957). This first period in Cologne was interrupted by a study visit (polio neutralisation) at the Karolinska Institute (Prof. Dr. Sven Gard), Stockholm, and a "compulsory assistant period" in Hamburg (clinical bacteriology and serology). From 1957 to 1959 he was a fellow of the Children's Hospital Research Foundation in Cincinnati, Ohio, with Prof. Dr. Albert B. Sabin and then a research associate with Prof. Dr. Frank L. Horsfall, Jr. and Prof. Dr. Igor Tamm at the Rockefeller Institute, New York. There he was Assistant Professor from 1961-1964. In 1965 he returned to Germany with his wife Gisela and their three children Carsten, Jens and Susanne, where he was head of department at the MPI for Virus Research in Tübingen from 1965-1966. In 1966 he was appointed to the chair of virology at the Justus Liebig University in Gießen and in 1972 to the likewise newly founded chair of virology at the University of Cologne. After his retirement, he was a visiting professor of virology at the Institute for Molecular Virology in Madison, Wisconsin.
Hans Joachim Eggers was a highly active founding member and honorary member of our Society and a member of numerous other scientific societies, including a member of the Senate of the Leopoldina.
Everyone who knew Prof. Eggers, especially his students, appreciated him as an outstanding scientist who always followed this calling with the greatest seriousness and sincerity. But with Hans Joachim Eggers we also lose a highly educated (Mozart expert), lovable person and always committed colleague and friend who was open to discussion. He will remain in our memory.
The funeral service will be on 21 May at 10.30 a.m. in the mourning hall of Melaten Cemetery, entrance Piusstraße, 50931 Cologne. The funeral will follow.
President of the GfV
Prof. Dr Jean Lindenmann
18 September 1924 in Zagreb
15 January 2015
Prof. Dr Jean Lindenmann
The first description of interferon in 1957 by Jean Lindenmann and Alick Isaacs is a milestone in biomedical research. Jean Lindenmann died on 15 January 2015, a few months after his 90th birthday, which he celebrated with close former colleagues on Lake Zurich.
Jean Lindenmann was born on 18 September 1924 in Zagreb, Yugoslavia (present-day Croatia).
He obtained the Matura type C at the Oberrealschule in Zurich and studied first physics and then medicine at the university. The dropping of the atomic bomb on Hiroshima prompted him to change his studies. He then worked as an assistant at the Hygiene Institute of the University under Prof. Hermann Mooser. In addition to bacteriological-diagnostic work, he was already concerned at that time with viral interference, whereby infection with a first virus protects against a second infection with the same or a completely different virus. The prevailing opinion was that the first infection would block or deplete important components in the infected cell, which would then no longer be available to the second virus. The budding researcher found in his own ingenious experiments that this was probably not true.
In 1956, he received a scholarship from the Swiss Academy of Medical Sciences to devote himself entirely to virology for a year at the National Institute for Medical Research in Mill Hill, London. He began a project on polioviruses under C.H. (later Sir Christopher) Andrewes and one day unexpectedly met Alick Isaacs, who was researching viral interference in the neighbouring laboratory. The two began an intense collaboration that culminated in the discovery of interferon within a few months. They found that the first virus causes infected cells to secrete a cellular substance that acts as a messenger to protect neighbouring cells from reinfection. Incidentally, the name interferon is owed to Lindenmann's old love of physics and its electrons, muons and mesons. Interferon with its manifold antiviral, antitumour and immunomodulatory effects became a success story.
Jean Lindenmann initially returned to the Hygiene Institute in Zurich as a senior assistant and in 1960 took up a position as a "second-class bacteriologist" at the then Federal Health Office in Bern. There, thanks to fortunate circumstances, he discovered that there was a hereditary resistance to influenza virus infections in certain laboratory mice. Initially, he thought it was a particularly good immune response. Later it became clear: it was interferon again. The resistance gene (MX1) is switched on by interferon. It also occurs naturally in humans, together with a second gene (MX2), which is part of the interferon response against HIV-1. From 1962, Jean Lindenmann worked as Visiting Assistant Professor at the Department of Microbiology at the University of Florida in Gainesville, where he began pioneering work on viral oncolysis and postoncolytic immunity. In 1964 he was appointed Extraordinarius for Experimental Microbiology at UZH, promoted to full professor in 1969 and in 1980 appointed full professor for Immunology and Virology and director of the institute of the same name. The institute becomes an El Dorado of creative thinking and research.
Jean Lindenmann was a gifted academic teacher who knew how to captivate his audience. Thanks to a natural curiosity, he was open to everything new. This resulted in an innovative textbook for beginners in immunology, structured in the style of a modern learning programme. He also knew how to address the general public clearly on current issues in medicine and the natural sciences. He was a member of the Research Council of the Swiss National Science Foundation and many other committees. He received numerous honours, such as the Georg Friedrich Goetz Prize in 1969, the Swiss Cancer Prize in 1964 and 1987 (together with Charles Weissmann), the Robert Koch Prize in 1973, the Marcel Benoist Prize in 1977 and the European Virology Award of the European Society of Virology in 2007.
After his retirement, Jean Lindenmann was able to devote himself entirely to his diverse interests in literature, art and music. He was deeply involved in the historical and sociological aspects of science and had no sympathy for the extreme view of certain sociologists who argued that scientific facts were merely based on social agreements. In his last autobiographical work he wrote: "Thus, I am outing myself as a naive realist. Sociologists and philosophers of science will dismiss me as an old fool. Too bad - tant pis pour moi - it was great fun". He will remain in our lasting memory, not as a fool,
but as an extraordinarily creative and critical personality with a great sense of humour.
Prof. Dr Axel Rethwilm
3 August 1959 in Bielefeld
29 July 2014
The Society of Virology mourns the death of Professor Dr Axel Rethwilm
Axel Rethwilm, holder of the Chair of Virology at the University of Würzburg, passed away in the night of 29 July at the age of only 54.
Axel Rethwilm was born on 3 August 1959 in Bielefeld. He studied human medicine at the University of Freiburg. After his doctorate, he began his scientific career in 1985 in the Department of Virus Research at the DKFZ Heidelberg.
In 1987, he moved to the Institute of Virology and Immunobiology at the University of Würzburg. His habilitation in virology followed in 1992 and his appointment as C3 professor of retrovirology in 1995. From 1998 to 2003 he was director of the Institute of Virology at the Technical University of Dresden. He then took over the Chair of Virology at the Institute of Virology and Immunobiology at the University of Würzburg.
Axel Rethwilm initially devoted himself to foamy viruses. He succeeded in the first molecular cloning and characterisation of a foamy virus genome. This was followed by groundbreaking scientific work on various aspects of the infection cycle of foamy viruses, including the infection process and tropism, the replication of the viral genome and the assembly of the viral particle. In addition, Axel Rethwilm developed a special scientific interest very early on regarding the development and use of foamy viruses as a vector platform for applications in the context of somatic gene therapy.
Basic virological science, application-oriented research and also clinical virological aspects, made him a very internationally recognised scientist and university lecturer.
The Funding of young scientists was very important to him. Cooperation with universities in Africa and the promotion of young scientists there were particularly close to his heart. He was the spokesperson for the first German-African Research Training Group, in which outstanding young researchers from Germany and Africa worked on the topic of "HIV, AIDS and associated infectious diseases". The German Research Foundation funded the Research Training Group from 2008.
Axel Rethwilm was a very active member of the GfV, also on the advisory board of our society. All those who knew him personally appreciated his always sincere, unconventional, open to discussion and at the same time always friendly manner.
We bid farewell to an outstanding scientist, and highly esteemed colleague and friend.
The burial of his urn will take place on 26 September at 1 p.m. at the Waldfriedhof in Würzburg.
Professor Karl Eduard Schneweis
24 April 1925 in Koblenz
7 February 2014
The Society of Virology mourns the death of Professor Karl Eduard Schneweis (Bonn). Born in Koblenz in 1925, he belonged to the founding generation of medical virology in Germany. After studying medicine in Bonn and Göttingen, he was an assistant physician at the Medical Examination Office in Hanover and at the Hygiene Institute in Hamburg.
At the Max Planck Institute for Tissue Engineering in Berlin-Dahlem, he developed new cell culture techniques with a special focus on histocompatibility antigens. From 1959, he established virological diagnostics at the University of Göttingen. In the process, he succeeded in serologically differentiating herpes simplex viruses and distinguishing between the two human simplex virus types for the first time. Professor Schneweis therefore deserves outstanding credit for the discovery of the herpes simplex virus type 2.
In 1968, he was appointed to Bonn to the Institute for Medical Microbiology and Immunology, then headed by Henning Brandis. The university hospital of the then federal capital thus got a virology department for the first time. In the 1970s, he established an efficient and highly respected medical virology in Bonn, whose research activities focused on the clinical picture and treatment of herpes virus infections. In the 1980s, the clinical virology of HIV infection became another field of work for Bonn virology. Professor Schneweis' laboratory was among the first institutions in Germany to offer complete HIV diagnostics. Therapy control in the use of early HIV drugs was initially carried out by cell culture experiments and was later switched to molecular biological methods.
Karl Eduard Schneweis was a sought-after member of many authoritative committees, working groups and professional societies. Until the end of his service, he headed the National Reference Centre for Herpesviruses in Bonn. He advised ministries and public health institutions and trained generations of students and graduates as an academic teacher.
With Karl Eduard Schneweis we lose a kind and highly respected colleague, mentor and friend.
Professor Reinhard Kurth
30 November 1942 in Dresden
2 February 2014 in Berlin
On 2 February 2014, virologist and physician Prof. Dr. Dr. h.c. Reinhard Kurth after a long, serious illness at the age of 71. He was an early member of Society of Virology (GfV).
After his licence to practise medicine, Reinhard Kurth initially devoted himself entirely to basic virological research in the field of immunobiology and pathogenesis of retroviruses.
When a human retrovirus (HIV) was identified as the causative agent of AIDS at the beginning of the 1980s, Reinhard Kurth, as head of the Department of Virology at the Paul Ehrlich Institute at that time, also became involved with great commitment in the work of clinical virology and combating viral diseases and played a decisive role in the rapid establishment of the first tests for detecting HIV infections.
In retrospect, it can probably be said that this was the moment in his life that steered him towards his outstanding work as a scientifically influenced shaper in the health system, who "saw public health precisely not as a label, but as a scientific challenge" - as Joachim Müller-Jung put it in his obituary in the Frankfurter Allgemeine Zeitung.
In this sense, Reinhard Kurth, as a virologist, first in his capacity as President of the Paul Ehrlich Institute, then as President of the Robert Koch Institute, structured and managed these federal institutes in the portfolio of the Federal Ministry of Health and shaped them far into the future.
However, Reinhard Kurth was also always concerned to inform the population comprehensively and in understandable terms, to educate them in crisis situations and to reassure them with competent information. Like no other, he brought the health policy aspects of virology to the outside world and ensured that they were perceived appropriately.
The two virological societies, Society of Virology and the German Association for the Control of Viral Diseases (DVV), always had an excellent, understanding and reliable partner in him when it came to the concerns of scientific and clinical virology and pay him great tribute and thanks.
Dr Regina Allwinn, MD, private lecturer
1 May 1961
25 November 2013 in Berlin
We mourn the loss of our GfV member and esteemed colleague
Private lecturer Dr. med. Regina Allwinn
who passed away after a serious illness at the age of 52 on 25 November 2013.
With Dr Allwinn, we are losing a lovely colleague who, as senior physician and head of the travel medicine vaccination outpatient clinic, worked with great dedication for the well-being of patients for over 17 years at Frankfurt University Hospital.
Der Beratung von Reisenden in der Impfambulanz und der Erforschung von Tropenviren galt ihre besondere Leidenschaft. Die Synthese aus Virologie und Reisemedizin wie auch die Verknüpfung von Familie und Beruf hatten für Frau Dr. Allwinn einen hohen Stellenwert. Mit ihr verlieren wir nicht nur eine hervorragende klinische Virologin, sondern auch eine humorvolle und lebensfrohe Kollegin, die uns durch ihre ehrliche und direkte Art oft zeigte, auf was es in der Infektionsmedizin und im Leben wirklich ankommt.
Wir sind betroffen und empfinden tiefe Trauer.
Für die Gesellschaft für Virologie (GfV)
Prof. Dr. med. Thomas Mertens
Prof. Dr. Rainer Laufs
Prof. Dr Heinz Schaller
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